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Tuesday, October 5, 2010

Bionovo : NIH Grant to Develop Drugs for the Treatment of Female-Specific Obesity and Metabolic Syndrome

Bionovo, Inc.Sept. 2, 2010 - Bionovo, Inc. (Nasdaq: BNVI, BNVID) announced that the U.S. National Institutes of Health (NIH), National Center for Complementary and Alternative Medicine (NCCAM) Small Business Technology Transfer Program, has approved and funded a grant to be shared by Bionovo and Dr. Dale Leitman from the University of California at Berkeley (UCB). The grant will fund the first phase in a planned multi-phase study to evaluate Bionovo's plant derived tissue selective estrogen receptor modulators for preventing obesity and the metabolic syndrome.

Menopause is associated with about a 10-15 pound weight gain and a redistribution of fat to the abdomen. The increase in abdominal fat, also known as visceral fat, is known to cause inflammation which can lead to metabolic syndrome. Metabolic syndrome represents a major public health burden because it increases the risk of cardiovascular disease and Type 2 diabetes. In the US, an estimated 25% of the population (50 million people) is classified as having this condition, which has led to enormous health care expenditures... Bionovo's Press Release -