July 12, 2010 - 7TM Pharma announced positive preclinical Positron Emission Tomography (PET) data in non human primates with their proprietary drug candidate TM38837, which was discovered at 7TM Pharma and is being developed for treatment of obesity, type 2 diabetes and related metabolic disorders. In line with a full range of other experiments, the data clearly demonstrate the principle feature of this first in class compound, namely that it is peripherally restricted. A direct comparison between TM38837 and rimonabant, a brain penetrant CB1 receptor antagonist, importantly exhibited a clear difference between their propensities to cross the blood brain barrier in favor of TM38837... 7TM Pharma's Press Release -
Wednesday, July 14, 2010
7TM Pharma : positron emission tomography preclinical research program to successfully demonstrate peripheral restriction of its CB1 receptor...
July 12, 2010 - 7TM Pharma announced positive preclinical Positron Emission Tomography (PET) data in non human primates with their proprietary drug candidate TM38837, which was discovered at 7TM Pharma and is being developed for treatment of obesity, type 2 diabetes and related metabolic disorders. In line with a full range of other experiments, the data clearly demonstrate the principle feature of this first in class compound, namely that it is peripherally restricted. A direct comparison between TM38837 and rimonabant, a brain penetrant CB1 receptor antagonist, importantly exhibited a clear difference between their propensities to cross the blood brain barrier in favor of TM38837... 7TM Pharma's Press Release -
