Feb. 27, 2008 - Athersys, Inc. (Nasdaq:ATHX) announced top-line results from its Phase 1 clinical trial of ATHX-105, its orally administered drug candidate for the treatment of obesity. ATHX-105 was well-absorbed, providing good drug exposures, well-tolerated up to high doses, and had no negative effect on cardiovascular, hematology or other clinical parameters. "We are pleased with the results of our Phase 1 study," said Gil Van Bokkelen, Ph.D., Athersys Chairman and CEO. "The data is in line with our expectations for ATHX-105, a highly selective 5HT2c agonist. As we have previously noted, we believe that high selectivity for 5HT2c relative to other receptors, such as 5HT2b and 5HT2a, is key to safety and tolerability. We believe that these results support the view that better selectivity results in superior tolerability for drugs in this class, which is an important factor for achieving effectiveness and patient compliance."... Athersys' Press Release -
