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Thursday, February 14, 2008

Phase I studies of Compellis Pharmaceuticals’ novel and patented obesity therapy

Boston, Mass., January 7, 2008 – Compellis Pharmaceuticals, an early-stage biopharmaceutical company developing novel mechanism-based therapeutics for the treatment of obesity, announced that its collaborator Pennington Biomedical Research Institute at Louisiana State University, with Principal Investigator Dr. Frank Greenway, MD, has received FDA approval to begin human clinical Phase I studies. Enrollment for the program will begin in the first quarter of 2008 with an expected completion date in the second half of the year...
CP404 is a calcium channel blocker used in a nasal formulation to block olfactory activity and alter behavior to reduce food intake. Compellis Pharmaceuticals has tested a series of like compounds and believes the effect can be seen in the overall class of calcium channel blockers. The advantage of CP404 is that it is a small molecule that is well tolerated in man and is readily manufactured...
Compellis' Press Release-